Newcastle disease virus-infected intact autologous tumor cell vaccine for adjuvant active specific immunotherapy of resected colorectal carcinoma.

@article{Ockert1996NewcastleDV,
  title={Newcastle disease virus-infected intact autologous tumor cell vaccine for adjuvant active specific immunotherapy of resected colorectal carcinoma.},
  author={Detlev Ockert and Volker Schirrmacher and Neal Beck and Erich Stoelben and Thorsten Ahlert and J Flechtenmacher and Egbert Hagm{\"u}ller and Rene Buchcik and Michelle Nagel and Hans Detlev Saeger},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={1996},
  volume={2 1},
  pages={21-8}
}
An active specific immunization (ASI) procedure with two types of autologous tumor cell vaccines (ATVs) is tested for adjuvant immunotherapy of resected colorectal carcinoma to provide preliminary information on local immunological skin responses, side effects, and 2-year survival rates. For vaccine preparation, the tumor-derived freshly isolated and cryopreserved cells were thawed, purified by Percoll density centrifugation, and depleted of tumor-infiltrating lymphocytes by immunomagnetic… CONTINUE READING