Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult.

@article{Braun1980NewbornRB,
  title={Newborn rabbit blood-brain barrier is selectively permeable and differs substantially from the adult.},
  author={Leon D Braun and Eain M. Cornford and William H. Oldendorf},
  journal={Journal of neurochemistry},
  year={1980},
  volume={34 1},
  pages={147-52}
}
Examination of blood-brain barrier (BBB) function by the intracarotid injection technique has been utilized in studies of newborn (6-30 h) and adult rabbits. The exclusion of mannitol (mol. wt. 182), dextran (mol. wt. 60,000-90,000), and indium-bound EDTA indicate that the newborn BBB has restrictive properties similar to the adult. At birth, saturable, carrier-mediated transport mechanisms are present, regulating the entry of glucose, amino acids, organic acids, purines, nucleosides, and… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 34 extracted citations

Similar Papers

Loading similar papers…