Newborn basal forebrain lesions disrupt cortical cytodifferentiation as visualized by rapid Golgi staining.

@article{Hhmann1991NewbornBF,
  title={Newborn basal forebrain lesions disrupt cortical cytodifferentiation as visualized by rapid Golgi staining.},
  author={C F H{\"o}hmann and K K Kwiterovich and Mary Lou Oster-Granite and Joseph T Coyle},
  journal={Cerebral cortex},
  year={1991},
  volume={1 2},
  pages={143-57}
}
We have previously shown that neonatal lesions of the basal forebrain cholinergic afferents result in transient cholinergic depletion concomitant with abnormal morphogenesis of cerebral cortex in Balb/CByJ mice (Höhmann et al., 1988). Here, we have utilized the rapid Golgi method to further characterize these previously observed abnormalities. We compared layer V pyramidal neurons in somatomotor cortex ipsi- and contralateral to the lesion at postnatal days (PND) 7 and 14. Quantitative… CONTINUE READING
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