New zinc(II) N4 tetradentate Schiff base complex: A potential cytotoxic metallodrug and simple precursor for the preparation of ZnO nanoparticles.


A novel Schiff base Zn(II) complex using a tetradentate Schiff base ligand was synthesized and characterized. The results of cytotoxicity assay revealed that the prepared complex induced cytotoxicity in a breast cancer cell line. Thus, the binding of the Zn(II) complex to human serum albumin (HSA) was investigated using spectroscopic and molecular docking… (More)
DOI: 10.1016/j.colsurfb.2017.10.026

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