New verticillane diterpenoids from Cespitularia taeniata.

  title={New verticillane diterpenoids from Cespitularia taeniata.},
  author={Jiun-Yang Chang and Ahmed Eid Fazary and Yu-Chi Lin and Tsong-Long Hwang and Y W Shen},
  journal={Chemistry & biodiversity},
  volume={9 3},
Chemical investigation of Cespitularia taeniata has led to the isolation of three new verticillanes, cespitulins E-G (1-3, resp.). The structures of these compounds were elucidated by spectroscopic analysis, especially HR-MS and 2D-NMR techniques. Compound 1 possesses a rare norverticillane skeleton with two adjacent OH groups at C(5) and C(6), while the seco-compound 2 with an aldehyde group at C(9) results from an unusual bond cleavage between C(9) and C(10). Pharmacological studies revealed… CONTINUE READING