New treatment strategies in large-vessel vasculitis

@article{Unizony2013NewTS,
  title={New treatment strategies in large-vessel vasculitis},
  author={Sebastian H. Unizony and John H. Stone and James R. Stone},
  journal={Current Opinion in Rheumatology},
  year={2013},
  volume={25},
  pages={3–9}
}
Purpose of reviewRecent advancements in the understanding of the pathogenesis of large-vessel vasculitis may broaden our currently limited therapeutic possibilities. This review summarizes the available evidence for new treatment strategies in this spectrum of diseases. Recent findingsInterleukin (IL) 6 appears to be an important mediator of the pathology in large-vessel vasculitis. IL-6 is upregulated in inflamed arteries of patients with giant cell arteritis and Takayasu arteritis, and serum… 

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