New thymine-based derivative of nitrogen mustards.

Abstract

This work deals with the synthesis of a new nitrogen mustard derivative based on thymine. To introduce the bis(2-chloroethyl)amine group to position 4 of the pyrimidine base, many strategies were explored and the desired compound was finally obtained, thanks to a synthetic pathway in five steps. 
DOI: 10.1080/15257770.2011.649330

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