New therapeutic option with N-acetylcysteine for primary sclerosing cholangitis: two case reports.

@article{Ozdil2011NewTO,
  title={New therapeutic option with N-acetylcysteine for primary sclerosing cholangitis: two case reports.},
  author={Burhan Ozdil and Arif Mansur Coşar and Hikmet Akkiz and Macit U. Sandikci and Can Keçe},
  journal={American journal of therapeutics},
  year={2011},
  volume={18 3},
  pages={e71-4}
}
Primary sclerosing cholangitis is a progressive, cholestatic hepatic disease of unknown etiology. It is characterized by progressive inflammation, destruction, and fibrosis of the intrahepatic and extrahepatic bile ducts. Several medical therapies have been tried such as penicilamin, colchicine, methatraxate, cyclosporine, tacrolimus, and ursodeoxycholic acid. Treatment with mucolytic agents in excessively high viscosity conditions appears to have an important role. N-acetylcysteine (NAC), as a… CONTINUE READING