New therapeutic applications for the anticoagulant, activated protein C.

Abstract

BACKGROUND Activated protein C (APC) is derived from its precursor, protein C (PC). Originally thought to be synthesised exclusively by the liver, recent reports have shown that PC is also produced by endothelial cells, smooth muscle cells, keratinocytes and some leukocytes. OBJECTIVE To provide an update on the emerging therapeutic effects of APC… (More)
DOI: 10.1517/14712598.8.8.1109

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