New therapeutic activity of metabolic enhancer piracetam in treatment of neurodegenerative disease: Participation of caspase independent death factors, oxidative stress, inflammatory responses and apoptosis.

@article{Verma2018NewTA,
  title={New therapeutic activity of metabolic enhancer piracetam in treatment of neurodegenerative disease: Participation of caspase independent death factors, oxidative stress, inflammatory responses and apoptosis.},
  author={Dinesh Kumar Verma and Sonam Gupta and Joyshree Biswas and Neeraj Joshi and Abhishek Kumar Singh and Parul Gupta and Shubhangini Tiwari and K Sivarama Raju and Swati Chaturvedi and Muhammad Wahajuddin and Sarika Singh},
  journal={Biochimica et biophysica acta},
  year={2018},
  volume={1864 6 Pt A},
  pages={2078-2096}
}
Piracetam, a nootropic drug that has been clinically used for decades but remains enigmatic due to no distinct understanding of its mechanism of action. The present study aimed to investigate the role of caspase independent pathway in piracetam mediated neuroprotection. LPS administration caused significant alterations in oxidative stress related parameters… CONTINUE READING