New tetramethylthiepinium (TMTI) for copper-free click chemistry.

Abstract

A new derivative of the strained 3,3,6,6-tetramethylthiacycloheptyne (TMTH) bearing a functional handle is reported. Following an optimized synthesis, the handle was introduced by mild alkylation of the sulphur atom. The resulting functionalized strained 4,5-didehydro-3,3,6,6-tetramethyl-2,3,6,7-tetrahydrothiepinium (TMTI) proved to be stable and underwent… (More)
DOI: 10.1039/c2cc35034c

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Cite this paper

@article{King2012NewT, title={New tetramethylthiepinium (TMTI) for copper-free click chemistry.}, author={Mathias King and Rachid Baati and Alain Wagner}, journal={Chemical communications}, year={2012}, volume={48 74}, pages={9308-9} }