New target antigens for anti-endothelial cell antibodies.

  title={New target antigens for anti-endothelial cell antibodies.},
  author={Pierre Youinou},
  volume={210 10},
Numerous connective tissue diseases, such as systemic lupus erythematosus (SLE), and infectious states, such as leprosy, are characterized by early vascular endothelial cell (EC) damage. There is substantial interest in the role of anti-EC antibodies (AECA) in such an injury. Due to the diversity of AECA-associated conditions, these autoantibodies are likely to be heterogeneous, and, therefore, identification of their antigens (Ag) to be difficult. They may be classified into three groups… CONTINUE READING


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