New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii.

  title={New sugar-mimic alkaloids from the pods of Angylocalyx pynaertii.},
  author={K. Yasuda and H. Kizu and T. Yamashita and Y. Kameda and A. Kato and R. Nash and G. Fleet and R. Molyneux and N. Asano},
  journal={Journal of natural products},
  volume={65 2},
Chromatographic separation of the pod extract of Angylocalyx pynaertii resulted in the isolation of 13 sugar-mimic alkaloids (1-13). The structures of the new alkaloids were elucidated by spectroscopic methods as the 6-O-beta-D-glucoside (10) and N-hydroxyethyl derivative (11) of 1,4-dideoxy-1,4-imino-D-arabinitol (DAB) (1), 1,6-dideoxynojirimycin (12), and 1,3,4-trideoxynojirimycin (13). 2,5-Imino-1,2,5-trideoxy-L-glucitol (7), 2,5-dideoxy-2,5-imino-D-fucitol (8), and beta-homofuconojirimycin… Expand
Oligoamide, a new lactam from the leaves of Angylocalyx oligophyllus
Effect of five-membered sugar mimics on mammalian glycogen-degrading enzymes and various glucosidases.
The inhibitory action of pyrrolidine alkaloid, 1,4-dideoxy-1,4-imino-D-ribitol, on eukaryotic DNA polymerases.
Chemo-enzymatic synthesis and glycosidase inhibitory properties of DAB and LAB derivatives.
Comparison of inhibitory activities and mechanisms of five mulberry plant bioactive components against α-glucosidase.
  • Hao He, Y. Lu
  • Chemistry, Medicine
  • Journal of agricultural and food chemistry
  • 2013