New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer.

@article{Forde2014NewSI,
  title={New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer.},
  author={Patrick M. Forde and Julie Renee Brahmer and Ronan Joseph Kelly},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2014},
  volume={20 9},
  pages={2244-8}
}
Recent discoveries that non-small cell lung cancer (NSCLC) can be divided into molecular subtypes based on the presence or absence of driver mutations have revolutionized the treatment of many patients with advanced disease. However, despite these advances, a majority of patients are still dependent on modestly effective cytotoxic chemotherapy to provide disease control and prolonged survival. In this article, we review the current status of attempts to target the epigenome, heritable… CONTINUE READING

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