New strategies for the synthesis of pyrimidine derivatives.

@article{Hill2008NewSF,
  title={New strategies for the synthesis of pyrimidine derivatives.},
  author={Matthew D. Hill and Mohammad Movassaghi},
  journal={Chemistry},
  year={2008},
  volume={14 23},
  pages={
          6836-44
        }
}
Recent advances in pyrimidine synthesis are described. Modification of conventional strategies involving N-C-N fragment condensation with 1,3-dicarbonyl derivatives remains a common theme in current literature. Other methods, including N-C fragment condensation strategies, provide reactive intermediates capable of intramolecular cyclization and formation of pyrimidine derivatives. These recently developed methodologies offer a valuable addendum to azaheterocycle synthesis. 

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