New strategies for prevention and treatment of noise-induced hearing loss

  title={New strategies for prevention and treatment of noise-induced hearing loss},
  author={Deepak K. Prasher},
  journal={The Lancet},
  • D. Prasher
  • Published 17 October 1998
  • Medicine
  • The Lancet
Hearing loss as a predictor for hearing protection attenuation among miners
The results of the adjusted regression models suggest that workers with hearing loss achieved significantly lower PARs than those without hearing loss, which brings into focus the potential benefit of fit checks to be included in hearing conservation programmes.
Systematic Transcriptome Analysis of Noise-Induced Hearing Loss Pathogenesis Suggests Inflammatory Activities and Multiple Susceptible Molecules and Pathways
This study indicates that the inflammatory response is involved in auditory organ changes in NIHL pathogenesis; moreover, several molecules and activities have essential and subtle influences that have translational potential for pharmacological intervention.
Prevalence, Awareness, and Factors Associated with Noise-induced Hearing Loss in Occupational Motorcyclists in Southwestern Nigeria
More than half of the study population was aware of noise-induced hearing loss and was able to link it to their profession, whereas 50% agreed that their occupation placed them at risk of hearing loss.
Metallurgy workers exposed to occupational noise had a statistically significant worsening in the audiometric thresholds in all frequencies evaluated, except for 6000 Hz.
Noise, the Silent Killer
Noise, the ‘unwanted sound’, is now realised as one of the most important environmental hazard in the present day industrial world. Exposure to noise is imminent, spearheaded by man’s casual attitude
Protective effects of auditory toughening on noise induced hearing loss in rats
(Au. D.) -- Towson University, 2008. Thesis approval page signed by thesis committee members and the Dean of the College of Graduate Studies and Research included in print copy of thesis.
Effect of vitamin E supplementation on carbogen-induced amelioration of noise induced hearing loss in man.
Results of audiometric studies revealed that breathing of carbogen prevented the development of temporary threshold shift; thereby reducing the risk of noise induced hearing loss.


Auditory System Plasticity and Regeneration
What is currently known about the principles and mechanisms of hair cell regeneration are synthesized and future research directions in this challenging area of hearing science are identified.
Noise, the most ubiquitous pollutant.
  • P. Alberti
  • Environmental Science, Medicine
    Noise & health
  • 1998
Excitatory amino acid antagonists protect cochlear auditory neurons from excitotoxicity
Results suggest that the acute swelling of radial dendrites primarily occurs via AMPA/kainate receptors, however, in radial d endrites contacting the inner hair cells on their modiolar side, NMDA receptors may be also involved.
The emergence of free radicals after acoustic trauma and strial blood flow.
The strange phenomenon that O2- emerged again at 2 h seemed ascribable to the re-circulation of strial blood flow after sound exposure, and the cause of its emergence at 5 min was obscure.
Pharmacological strategies for preventing cochlear damage induced by noise trauma.
Current experimental designs include strategies for protecting against injury and are primarily based on the fact that the metabolic state of the cochlea can determine the overall degree of hearing loss induced by noise.
The Protective Effects of Allopurinol and Superoxide Dismutase on Noise-Induced Cochlear Damage
Findings show that SOD-PEG and allopurinol may preserve cochlear sensitivity associated with noise exposure, which suggests that noise-induced damage to the cochlea may be related to the activity of FORs.
Effects of occupational exposure to organic solvents and noise on hearing.
Exposure to the studied solvents had a toxic effect on the auditory system and that an interaction between noise and toluene took place, suggesting a central auditory pathway involvement in the hearing losses observed.