New strategies for fluorescent probe design in medical diagnostic imaging.

@article{Kobayashi2010NewSF,
  title={New strategies for fluorescent probe design in medical diagnostic imaging.},
  author={Hisataka Kobayashi and Mikako Ogawa and Raphael E Alford and Peter L. Choyke and Yasuteru Urano},
  journal={Chemical reviews},
  year={2010},
  volume={110 5},
  pages={2620-40}
}
In vivo medical imaging has made great progress due to advances in the engineering of imaging devices and developments in the chemistry of imaging probes. Several modalities have been utilized for medical imaging, including X-ray radiography and computed tomography (X-ray CT), radionuclide imaging using single photons and positrons, magnetic resonance imaging (MRI), ultrasonography (US), and optical imaging. To extract more information from imaging, “con-