New signaling pathways govern the host response to C. albicans infection in various niches.

@article{Liu2015NewSP,
  title={New signaling pathways govern the host response to C. albicans infection in various niches.},
  author={Yaoping Liu and Amol Carl Shetty and Jennifer Schwartz and L Lat{\'e}y Bradford and Wenjie Xu and Qyunh T Phan and Priti Kumari and Anup Mahurkar and Aaron P. Mitchell and Jacques Ravel and Claire M. Fraser and Scott G. Filler and Vincent M. Bruno},
  journal={Genome research},
  year={2015},
  volume={25 5},
  pages={679-89}
}
Candida albicans, the major invasive fungal pathogen of humans, can cause both debilitating mucosal infections and fatal invasive infections. Understanding the complex nature of the host-pathogen interaction in each of these contexts is essential to developing desperately needed therapies to treat fungal infections. RNA-seq enables a systems-level understanding of infection by facilitating comprehensive analysis of transcriptomes from multiple species (e.g., host and pathogen) simultaneously… CONTINUE READING
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