New selective ligands of human cloned melatonin MT1 and MT2 receptors


Melatonin has a key role in the circadian rhythm relay to periphery organs. Melatonin exerts its multiple roles mainly through two seven transmembrane domain, G-coupled receptors, namely MT1 or MT2 receptors. A pharmacological characterization of these human cloned melatonin hMT1 and hMT2 receptors stably expressed in HEK-293 or CHO cells is presented using… (More)
DOI: 10.1007/s00210-003-0751-2


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@article{Audinot2003NewSL, title={New selective ligands of human cloned melatonin MT1 and MT2 receptors}, author={Val{\'e}rie Audinot and François Mailliet and Chantal Lahaye-Brasseur and Anne Bonnaud and Aude Le Gall and Christophe Amoss{\'e} and Sandra Dromaint and M. {\'A}ngeles Prieto - Rodr{\'i}guez and Nadine Nagel and J M Galizzi and Beno{\^i}t Malpaux and G{\'e}rald Guillaumet and Daniel Lesieur and François Lefoulon and Pierre Renard and Philippe Delagrange and Jean A. Boutin}, journal={Naunyn-Schmiedeberg's Archives of Pharmacology}, year={2003}, volume={367}, pages={553-561} }