New secreted toxins and immunity proteins encoded within the Type VI secretion system gene cluster of Serratia marcescens

@inproceedings{English2012NewST,
  title={New secreted toxins and immunity proteins encoded within the Type VI secretion system gene cluster of Serratia marcescens},
  author={Grant English and Katharina Trunk and Vincenzo A. Rao and Velupillai Srikannathasan and William N. Hunter and Sarah J Coulthurst},
  booktitle={Molecular microbiology},
  year={2012}
}
Protein secretion systems are critical to bacterial virulence and interactions with other organisms. The Type VI secretion system (T6SS) is found in many bacterial species and is used to target either eukaryotic cells or competitor bacteria. However, T6SS-secreted proteins have proven surprisingly elusive. Here, we identified two secreted substrates of the antibacterial T6SS from the opportunistic human pathogen, Serratia marcescens. Ssp1 and Ssp2, both encoded within the T6SS gene cluster… CONTINUE READING
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