New roles for astrocytes: redefining the functional architecture of the brain.

  title={New roles for astrocytes: redefining the functional architecture of the brain.},
  author={Maiken Nedergaard and Bruce R Ransom and Steven A Goldman},
  journal={Trends in neurosciences},
  volume={26 10},
Astrocytes have traditionally been considered ancillary, satellite cells of the nervous system. However, work over the past decade has revealed that they interact with the vasculature to form a gliovascular network that might organize not only the structural architecture of the brain but also its communication pathways, activation, thresholds and plasticity. The net effect is that astroglia demarcate gray matter regions, both cortical and subcortical, into functional compartments whose internal… CONTINUE READING
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