New roles for astrocytes: Regulation of synaptic transmission

@article{Newman2003NewRF,
  title={New roles for astrocytes: Regulation of synaptic transmission},
  author={E. A. Newman},
  journal={Trends in Neurosciences},
  year={2003},
  volume={26},
  pages={536-542}
}
  • E. A. Newman
  • Published 2003
  • Medicine, Biology
  • Trends in Neurosciences
  • Abstract Although glia often envelop synapses, they have traditionally been viewed as passive participants in synaptic function. Recent evidence has demonstrated, however, that there is a dynamic two-way communication between glia and neurons at the synapse. Neurotransmitters released from presynaptic neurons evoke Ca2+ concentration increases in adjacent glia. Activated glia, in turn, release transmitters, including glutamate and ATP. These gliotransmitters feed back onto the presynaptic… CONTINUE READING
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