New roles for INSL3 in adults.


Insulin-like factor 3 (INSL3) is produced primarily by testicular Leydig cells and acts by binding to its specific G-protein-coupled receptor, RXFP2 (relaxin family peptide 2). INSL3 is involved in testicular descent during fetal development, and mutations in the INSL3 and RXFP2 genes cause cryptorchidism. The physiological role of INSL3 in adults is not… (More)
DOI: 10.1111/j.1749-6632.2008.03787.x


Cite this paper

@article{Ferlin2009NewRF, title={New roles for INSL3 in adults.}, author={A Ferlin and Anastasia Pepe and Lisa Gianesello and Andrea Garolla and Shu Feng and Arianna Facciolli and Roy Morello and Alexander I. Agoulnik and Carlo Foresta}, journal={Annals of the New York Academy of Sciences}, year={2009}, volume={1160}, pages={215-8} }