New progestogens: a review of their effects in perimenopausal and postmenopausal women.

@article{SitrukWare2004NewPA,
  title={New progestogens: a review of their effects in perimenopausal and postmenopausal women.},
  author={R{\'e}gine L Sitruk-Ware},
  journal={Drugs & aging},
  year={2004},
  volume={21 13},
  pages={
          865-83
        }
}
The progestins have different pharmacological properties depending upon the parent molecule, usually testosterone or progesterone, from which they are derived. Very small structural changes in the parent molecule may induce considerable differences in the activity of the derivative. In postmenopausal women with an intact uterus, progestins are used in combination with estrogen as hormone-replacement therapy (HRT). The development of new generations of progestins with improved selectivity… CONTINUE READING

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