New polymorphic microsatellite markers in the human MHC class III region.

@article{Matsuzaka2001NewPM,
  title={New polymorphic microsatellite markers in the human MHC class III region.},
  author={Yasunari Matsuzaka and Satoshi Makino and Koji Nakajima and Maiko Tomizawa and A. A. Kompiang Oka and Seiamak Bahram and Jerzy K. Kulski and Gen Tamiya and Hidetoshi Inoko},
  journal={Tissue antigens},
  year={2001},
  volume={57 5},
  pages={397-404}
}
The human major histocompatibility complex (MHC) class III region spanning approximately 760 kb is characterized by a remarkably high gene density with 59 expressed genes (one gene every 12.9 kb). Recently, susceptibility loci to numerous diseases, such as Graves disease, Crohn disease, and SLE have been suggested to be localized to this region, as assessed by associations mainly with genetic polymorphisms of TNF and TNF-linked microsatellite loci. However, it has been difficult to precisely… CONTINUE READING
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