New polychlorinated amino acid derivatives from the marine sponge Dysidea herbacea

@article{Unson1993NewPA,
  title={New polychlorinated amino acid derivatives from the marine sponge Dysidea herbacea},
  author={M. D. Unson and C. B. Rose and D. Faulkner and L. Brinen and J. R. Steiner and J. Clardy},
  journal={Journal of Organic Chemistry},
  year={1993},
  volume={58},
  pages={6336-6343}
}
A new series of polychlorinated amino acid derivatives were isolated from the tropical marine sponge Dysidea herbacea (Dictyoceratida). Two major hexachlorinated metabolites, dysideathiazole (4) and N-methyldysideathiazole (5), and a minor pentachlorinated compound, 10-dechloro-N-methyldysideathizole (6), were isolated from a specimen from Pohnpei. 10-Dechlorodysideathiazole (7) was isolated as a minor constituent of a Palauan specimen, together with the major metabolites 9,10-didechloro-N… Expand
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