New phenolic compounds from the seeds of Nigella glandulifera and their inhibitory activities against human cancer cells.

@article{Sun2015NewPC,
  title={New phenolic compounds from the seeds of Nigella glandulifera and their inhibitory activities against human cancer cells.},
  author={Lu Sun and Yu-ming Liu and Bao-quan Chen and Qing-Hua Liu},
  journal={Bioorganic & medicinal chemistry letters},
  year={2015},
  volume={25 18},
  pages={3864-6}
}
Four phenolic compounds, including two new ones, Nigephenol A and B (1-2), and a new natural product, Nigephenol C (3), were isolated from the seeds of Nigella glandulifera. Their structures were elucidated on the basis of spectroscopic analyses using HR-ESI-MS, 1D and 2D NMR spectra. All compounds were evaluated by MTT method for in vitro cytotoxicity… CONTINUE READING