New pharmacotherapy for epilepsy.

  title={New pharmacotherapy for epilepsy.},
  author={Asla Pitkanen},
  journal={IDrugs : the investigational drugs journal},
  volume={7 5},
  • Asla Pitkanen
  • Published 2004 in IDrugs : the investigational drugs journal
In the majority of cases, epilepsy develops in three phases: (i) initial brain damaging insult (eg, head trauma, stroke, status epilepticus), resulting in (ii) epileptogenesis, which in turn leads to (iii) recurrent seizures (epilepsy). The current treatment of epilepsy, however, focuses exclusively on the prevention or suppression of seizures, ie, the end result of the disease process. Recent findings regarding the sequence of neurobiological changes leading to epilepsy and its molecular basis… CONTINUE READING