New pharmacological approaches for the treatment of alcoholism

@article{Soyka2006NewPA,
  title={New pharmacological approaches for the treatment of alcoholism},
  author={M. Soyka and S. R{\"o}sner},
  journal={Expert Opinion on Pharmacotherapy},
  year={2006},
  volume={7},
  pages={2341 - 2353}
}
  • M. Soyka, S. Rösner
  • Published 2006
  • Medicine
  • Expert Opinion on Pharmacotherapy
    • Pharmacological relapse prevention in alcoholism is a rather new clinical field with few drugs being available. Acamprosate, acting predominantly via glutamatergic pathways, and the opioid receptor antagonist naltrexone, were both shown to be efficient in improving rates for continuous abstinence, and not relapsing to heavy drinking in a number of clinical trials and meta-analyses. There are conflicting data on both drugs, especially for acamprosate, according to some recent US studies. However… CONTINUE READING
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    References

    SHOWING 1-10 OF 142 REFERENCES
    Efficacy of naltrexone and acamprosate for alcoholism treatment: a meta-analysis.
    • 373
    Neuropharmacological treatments for alcoholism: scientific basis and clinical findings
    • 160
    • Highly Influential
    Update on anticonvulsants for the treatment of alcohol withdrawal.
    • 108
    Pharmacological treatment of alcohol dependence: a review of the evidence.
    • 437
    Double-Blind Clinical Trial of Sertraline Treatment for Alcohol Dependence
    • 116
    The use of divalproex in alcohol relapse prevention: a pilot study.
    • 102
    Naltrexone in the treatment of alcoholism.
    • 73
    Naltrexone and cognitive behavioral therapy for the treatment of outpatient alcoholics: results of a placebo-controlled trial.
    • 309
    A double-blind, placebo-controlled pilot study of carbamazepine for the treatment of alcohol dependence.
    • 123
    Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism: a double-blind, placebo-controlled study.
    • 345
    • PDF