New pharmacological approaches for the treatment of alcoholism

  title={New pharmacological approaches for the treatment of alcoholism},
  author={M. Soyka and S. R{\"o}sner},
  journal={Expert Opinion on Pharmacotherapy},
  pages={2341 - 2353}
  • M. Soyka, S. Rösner
  • Published 2006
  • Medicine
  • Expert Opinion on Pharmacotherapy
  • Pharmacological relapse prevention in alcoholism is a rather new clinical field with few drugs being available. Acamprosate, acting predominantly via glutamatergic pathways, and the opioid receptor antagonist naltrexone, were both shown to be efficient in improving rates for continuous abstinence, and not relapsing to heavy drinking in a number of clinical trials and meta-analyses. There are conflicting data on both drugs, especially for acamprosate, according to some recent US studies. However… CONTINUE READING
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