New pharmacologic therapies in chronic hepatitis B.

  title={New pharmacologic therapies in chronic hepatitis B.},
  author={Chanunta Hongthanakorn and Anna S. F. Lok},
  journal={Gastroenterology clinics of North America},
  volume={39 3},
Approximately 350 million persons worldwide are chronically infected with hepatitis B, which can result in cirrhosis, liver failure, and hepatocellular carcinoma. Currently, 2 interferons and 5 nucleos(t)ide analogues have been approved for the treatment of chronic hepatitis B (CHB). This article discusses the mechanisms of action, pharmacokinetics, optimal… CONTINUE READING