New perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma.

@article{Walker2011NewPR,
  title={New perspectives regarding β(2) -adrenoceptor ligands in the treatment of asthma.},
  author={Julia K. L. Walker and Raymond B. Penn and Nicola Alexander Hanania and Burton F Dickey and Richard A. Bond},
  journal={British journal of pharmacology},
  year={2011},
  volume={163 1},
  pages={18-28}
}
In the last two decades several significant changes have been proposed in the receptor theory that describes how ligands can interact with G protein-coupled receptors (GPCRs). Here we briefly summarize the evolution of receptor theory and detail recent prominent advances. These include: (i) the existence of spontaneously active GPCRs that are capable of… CONTINUE READING