New perspectives on endothelin-1 in atherosclerosis and diabetes mellitus.

Abstract

Endothelin-1 (ET-1) is a vasoconstrictor, proinflammatory and proliferative endothelial cell-derived peptide that is of significant importance in the regulation of vascular function. It is involved in the development of endothelial dysfunction including important interactions with nitric oxide. The expression and functional effects of ET-1 and its receptors… (More)
DOI: 10.1016/j.lfs.2012.03.029

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