New perspectives in the functional role of GABAa channel heterogeneity

@article{Vicini2007NewPI,
  title={New perspectives in the functional role of GABAa channel heterogeneity},
  author={S. Vicini},
  journal={Molecular Neurobiology},
  year={2007},
  volume={19},
  pages={97-110}
}
  • S. Vicini
  • Published 2007
  • Medicine, Biology
  • Molecular Neurobiology
  • Abstractγ-Aminobutyric acid A (GABAA) channels responsible for inhibitory synaptic transmission possess a consistent heterogeneity of structure in terms of distinct constitutive subunits. During the past 10 years, considerable progress has been made in understanding the magnitude of this large diversity. Structural requirements for clinically important drugs such as benzodiazepines and barbiturates have been elucidated, and the anatomical distribution in distinct neuronal populations and the… CONTINUE READING

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    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 92 REFERENCES
    Molecular biology of GABAA receptors
    • 931
    • PDF
    From ion currents to genomic analysis: Recent advances in GABAA receptor research
    • 482
    • Highly Influential
    Structure and pharmacology of vertebrate GABAA receptor subtypes.
    • 223
    • Highly Influential
    Physiological evidence for two distinct GABAA responses in rat hippocampus
    • 323
    Insensitivity to anaesthetic agents conferred by a class of GABAA receptor subunit
    • 406
    δ Subunit Inhibits Neurosteroid Modulation of GABAAReceptors
    • 151
    • PDF
    Differences in Synaptic GABAA Receptor Number Underlie Variation in GABA Mini Amplitude
    • 427
    • Highly Influential
    • PDF
    Cerebellar granule cells in vitro recapitulate the in vivo pattern of GABAA-receptor subunit expression.
    • 68