New penicillide derivatives isolated from Penicillium simplicissimum

@article{Komai2005NewPD,
  title={New penicillide derivatives isolated from Penicillium simplicissimum},
  author={Shin-ichirou Komai and Tomoo Hosoe and Takeshi Itabashi and Koohei Nozawa and Takashi Yaguchi and Kazutaka Fukushima and Ken-ichi Kawai},
  journal={Journal of Natural Medicines},
  year={2005},
  volume={60},
  pages={185-190}
}
Two new penicillide derivatives, secopenicillides A (3) and B (4), were isolated along with penicillide (1) and purpactin A (2), and altenusin (5) and dehydroaltenusin (6), the antifungal substances of this fungus, from the extract of Penicillium simplicissimum IFM 53375. The absolute structures of 3 and 4 were determined by spectroscopic investigation and chemical correlation to penicillide (1). The absolute configuration of purpactin A (2) was determined by the chemical method. 

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