New oral anticoagulants for non-valvular atrial fibrillation: harder to handle than expected.

@article{Shurlock2014NewOA,
  title={New oral anticoagulants for non-valvular atrial fibrillation: harder to handle than expected.},
  author={Barry Shurlock},
  journal={European heart journal},
  year={2014},
  volume={35 28},
  pages={1825-36}
}
Many clinicians who manage coagulation therapy have long had a love–hate relationship with the vitamin K antagonist warfarin. The complexity of its use, the intricacies of INR—as well as its use as a rat poison!—have also done little to endear it to patients. Physicians with a passion for pharmacokinetics, and especially food and drug interactions, may have been happily engaged with the drug, but others who want to help their patients with minimum complication have long sought agents like the… CONTINUE READING