New nucleoside analogs for patients with hematological malignancies.

@article{Robak2011NewNA,
  title={New nucleoside analogs for patients with hematological malignancies.},
  author={Tadeusz Robak},
  journal={Expert opinion on investigational drugs},
  year={2011},
  volume={20 3},
  pages={343-59}
}
INTRODUCTION In the last few years, several new purine and pyrimidine nucleoside analogs have been synthesized and made available for both preclinical studies and clinical trials. AREAS COVERED This article summarizes recent achievements in the mechanism of action, pharmacological properties and clinical activity and toxicity as well as the emerging role of newer purine and pyrimidine nucleoside analogs potentially active in lymphoid and myeloid malignancies. A literature review was conducted… CONTINUE READING

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