New nonparametric confidence intervals for the Youden index.

  title={New nonparametric confidence intervals for the Youden index.},
  author={Haochuan Zhou and Gengsheng Qin},
  journal={Journal of biopharmaceutical statistics},
  volume={22 6},
The Youden index, a main summary index for the receiver operating characteristic (ROC) curve, is a comprehensive measurement for the effectiveness of a diagnostic test. For a continuous-scale diagnostic test, the optimal cut point for positive disease is the cut point leading to the maximization of the sum of sensitivity and specificity. Finding the Youden index of the test is equivalent to maximize the sum of sensitivity and specificity for all the possible values of the cut point. In this… CONTINUE READING

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Showing 1-10 of 15 references

Confidence Intervals for the Youden Index and Corresponding Optimal Cut-Point

Communications in Statistics - Simulation and Computation • 2007
View 5 Excerpts
Highly Influenced

Statistical inference on “r·specificity+sensitivity

N. Barkan
(in Hebrew). PhD thesis, • 2001
View 6 Excerpts
Highly Influenced

A solution for the most basic optimization problem associated with an ROC curve.

Statistical methods in medical research • 2006
View 2 Excerpts

Estimation of the Youden Index and its associated cutoff point.

Biometrical journal. Biometrische Zeitschrift • 2005
View 1 Excerpt

The Statistical Evaluation of Medical Tests for Classification and Prediction

M. S. Pepe
View 1 Excerpt