New nephron development in goldfish (Carassius auratus) kidneys following repeated gentamicin-induced nephrotoxicosis.

@article{Salice2001NewND,
  title={New nephron development in goldfish (Carassius auratus) kidneys following repeated gentamicin-induced nephrotoxicosis.},
  author={Christopher J Salice and J S Rokous and Andrew S Kane and Renate Reimschuessel},
  journal={Comparative medicine},
  year={2001},
  volume={51 1},
  pages={56-9}
}
Renal development in mammalian kidneys can only be studied in embryonic animals. Hence, research in this area is hampered by the need to maintain pregnant animals and by the small size of the embryonic kidney. Here, we describe a goldfish (Carassius auratus) model for studying renal repair and nephron development in an adult animal. Previous studies have indicated that chemically induced nephrotoxicosis in goldfish is followed by new nephron development. We tested the hypothesis that new… CONTINUE READING

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