New natural intergenotypic (2/5) recombinant of hepatitis C virus.

@article{LegrandAbravanel2007NewNI,
  title={New natural intergenotypic (2/5) recombinant of hepatitis C virus.},
  author={Florence Legrand-Abravanel and Julie Claudinon and Florence Nicot and Martine Dubois and Sabine Chapuy-Regaud and Karine Sandres-Saun{\'e} and Christophe Pasquier and Jacques Izopet},
  journal={Journal of virology},
  year={2007},
  volume={81 8},
  pages={
          4357-62
        }
}
A 9.2-kb sequence from a hepatitis C virus (HCV) strain found in southwest France was compared to sequences from reference strains in HCV sequence databases. We found a recombinant virus with genotype 2 at the 5' end and genotype 5 at the 3' end. The crossover point was located between genes NS2 and NS3. Recombination between HCV genotypes must now be considered in studies on HCV epidemiology and evolution and in predictions of the virus response to antiviral therapy. Knowing the location of… CONTINUE READING

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