New mutations in flagellar motors identified by whole genome sequencing in Chlamydomonas

  title={New mutations in flagellar motors identified by whole genome sequencing in
  author={Huawen Lin and Nicholas P Nauman and Alison J. Albee and Silas Hsu and Susan K. Dutcher},
The building of a cilium or flagellum requires molecular motors and associated proteins that allow the relocation of proteins from the cell body to the distal end and the return of proteins to the cell body in a process termed intraflagellar transport (IFT). IFT trains are carried out by kinesin and back to the cell body by dynein. We used whole genome sequencing to identify the causative mutations for two temperature-sensitive flagellar assembly mutants in Chlamydomonas and validated the… CONTINUE READING


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