New molecular complexes of heterocyclic bis-adducts with bacterial lectins: synthesis and structure-activity relationship studies.

Abstract

A strongly antitumour effect has been discovered for lectins of Bacillus bacteria [Bacillus subtilis 668(1 + 2)IMV, Bacillus polymyxa 102(1 + 2) KGU] and for their molecular complexes with some heterocyclic bis-adducts of unsubstituted benzimidazole and 6-methyluracile for the first time. These were tested on the tumours: Lymphosarcoma Plissa, Sarcoma 45… (More)

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@article{Welchinskaya1999NewMC, title={New molecular complexes of heterocyclic bis-adducts with bacterial lectins: synthesis and structure-activity relationship studies.}, author={H V Welchinskaya and Ivan Kuzmenko and I. G. Kudryavtseva and N I Sharikina and Ekaterina A Kovalenko and Victor Podgorsky}, journal={International journal of biological macromolecules}, year={1999}, volume={26 4}, pages={243-8} }