New miniaturized hollow-fiber bioreactor for in vivo like cell culture, cell expansion, and production of cell-derived products.

@article{Glckner2001NewMH,
  title={New miniaturized hollow-fiber bioreactor for in vivo like cell culture, cell expansion, and production of cell-derived products.},
  author={Helge Gl{\"o}ckner and Hans David Lemke},
  journal={Biotechnology progress},
  year={2001},
  volume={17 5},
  pages={828-31}
}
We have developed a miniaturized hollow-fiber bioreactor system for mammalian cell culture with a volume of 1 mL. Cell and medium compartments of the bioreactor are separated by a semipermeable membrane, and oxygenation of the cell compartment is accomplished using an oxygenation membrane. As a result of the geometry of the transparent housing, cells can be… CONTINUE READING