New methods of structure refinement for macromolecular structure determination by NMR.

@article{Clore1998NewMO,
  title={New methods of structure refinement for macromolecular structure determination by NMR.},
  author={G Marius Clore and Angela M. Gronenborn},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1998},
  volume={95 11},
  pages={5891-8}
}
Recent advances in multidimensional NMR methodology have permitted solution structures of proteins in excess of 250 residues to be solved. In this paper, we discuss several methods of structure refinement that promise to increase the accuracy of macromolecular structures determined by NMR. These methods include the use of a conformational database potential and direct refinement against three-bond coupling constants, secondary 13C shifts, 1H shifts, T1/T2 ratios, and residual dipolar couplings… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 51 extracted citations

References

Publications referenced by this paper.

Clore and Gronenborn Proc

  • G. M. Clore, A. M. Gronenborn, +5 authors 313–318. 5898 Colloquium Paper
  • Natl. Acad. Sci. USA 95
  • 1998
1 Excerpt

Similar Papers

Loading similar papers…