New method to enhance ajmalicine production in Catharanthus roseus cell cultures based on the use of cyclodextrins

@article{Almagro2010NewMT,
  title={New method to enhance ajmalicine production in Catharanthus roseus cell cultures based on the use of cyclodextrins},
  author={Lorena Almagro and A. J. L{\'o}pez Perez and Mar{\'i}a {\'A}ngeles Pedre{\~n}o},
  journal={Biotechnology Letters},
  year={2010},
  volume={33},
  pages={381-385}
}
The joint use of cyclodextrins and methyljasmonate, when accompanied by a short exposure to UV, enhanced extracellular ajmalicine accumulation to 1040 ± 26.6 mg/l in suspension cultured cells of Catharanthus roseus. The success of this strategy is due to the use of cyclodextrins, which not only induce ajmalicine biosynthesis but also promote adduct formation. This removes ajmalicine from the medium, reduces feedback inhibition and ajmalicine degradation, and allows its accumulation in the… CONTINUE READING
14 Citations
11 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 14 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 11 references

Organic growth factor requirements of tobacco tissue cultures

  • EM Linsmaier, F Skoog
  • Physiol Plant
  • 1965
Highly Influential
2 Excerpts

Similar Papers

Loading similar papers…