New method of estimating wavelength-dependent optical path length ratios for oxy- and deoxyhemoglobin measurement using near-infrared spectroscopy.

@article{Umeyama2009NewMO,
  title={New method of estimating wavelength-dependent optical path length ratios for oxy- and deoxyhemoglobin measurement using near-infrared spectroscopy.},
  author={Shinji Umeyama and Toru Yamada},
  journal={Journal of biomedical optics},
  year={2009},
  volume={14 5},
  pages={054038}
}
In near-infrared spectroscopy (NIRS), concentration changes in oxy- and deoxyhemoglobin are calculated using an attenuation change of the measurement light and by solving a linear equation based on the modified Lambert-Beer law. While solving this equation, we need to know the wavelength-dependent mean optical path lengths of the measurement lights. However, it is very difficult to know these values by a continuous-wave-type (CW-type) system. We propose a new method of estimating wavelength… CONTINUE READING