New method development for nanoparticle extraction of water-soluble beta-(1-->3)-D-glucan from edible mushrooms, Sparassis crispa and Phellinus linteus.

  title={New method development for nanoparticle extraction of water-soluble beta-(1-->3)-D-glucan from edible mushrooms, Sparassis crispa and Phellinus linteus.},
  author={Hyuk-Gu Park and Youn Young Shim and Seung-Oh Choi and Won Mok Park},
  journal={Journal of agricultural and food chemistry},
  volume={57 6},
Sparassis crispa and Phellinus linteus are edible/medicinal mushrooms that have remarkably high contents of beta-(1-->3)-D-glucan, which acts as a biological response modifier, but difficulty in cultivating the fruiting bodies and extraction of beta-D-glucan have restricted detailed studies. Therefore, a novel process for nanoparticle extraction of Sparan, the beta-D-glucan from Sparassis crispa, and Phellin, the beta-D-glucan from Phellinus linteus, has been investigated using insoluble… 

Figures and Tables from this paper

Alginate-Derived Elicitors Enhance β-Glucan Content and Antioxidant Activities in Culinary and Medicinal Mushroom, Sparassis latifolia
It is demonstrated that alginate oligosaccharides extracted from brown algae may be useful as an elicitor to enhance the nutritional value of mushrooms and significantly stimulate β-glucan production in cauliflower mushroom.
Improved purity and immunostimulatory activity of β-(1→3)(1→6)-glucan from Pleurotus sajor-caju using cell wall-degrading enzymes.
Purified β-glucan was able to effectively up-regulate the functions of macrophages such as nitric oxide (NO) and tumor necrosis factor (TNF-α) production.
Structural Elucidation and Immune-Enhancing Effects of Novel Polysaccharide from Grifola frondosa
It is suggested that 20-30 μm size is the suitable size of G. frondosa that can be used as a health supplement and food additive to act as an immune booster, hypotensive agent, and hypoglycemic agent.
α-Glucosidase and aldose reductase inhibitory activities from the fruiting body of Phellinus merrillii.
It is demonstrated that PM may be a good source for lead compounds as alternatives for antidiabetic agents currently used and found the strong α-glucosidase and aldose reductase activities showed in the ethanol extracts of PM.
Effect of Barley β-Glucan on the Gluten Polymerization Process in Dough during Heat Treatment.
Barley (Hordeum vulgare L.) β-glucan (BBG) is of interest as a result of its health benefits, but BBG presents significant disruptions on the gluten network, with a negative impact on food texture.
꽃송이버섯(Sparassis crispa) 추출물의 면역세포 활성화 및 항암 효과
It is shown that S. crispa soluble β-glucan was able to stimulate TNF-α and IL-1β production through NF-kB activation in Raw 264.7 cells and extracts could not only enhance T NF-α production in raw cells, but also suppress tumor growth in vivo.
Influence of Maitake (Grifola frondosa) Particle Sizes on Human Mesenchymal Stem Cells and In Vivo Evaluation of Their Therapeutic Potential
G. frondosa is effective for enhanced osteogenesis and can be utilized as a natural, edible, and osteogenic agent.


Preparation method and their materials of soluble nano-sized beta Glucan from medicinal mushroom
The present invention the particle size of the water-soluble nanosized from the fruiting bodies and mycelia of Phellinus (Phellinus linteus), zinnia mushrooms (Sparassis crispa), Ganoderma lucidum
Water - solubility of β - Glucans in Various Edible Mushrooms
The amount of β-glucans in 12 edible mushroom species was determined and their water-solubility was assessed. A large variability in β-glucan content was observed in the mushroom species, ranging
Antitumor 1,3-beta-glucan from cultured fruit body of Sparassis crispa.
Polysaccharide fractions prepared from the cultured S. crispa showed antitumor activity to the solid form of Sarcoma 180 in ICR mice with strong vascular dilation and hemorrhage reaction and enhanced hematopoietic response to cyclophosphamide induced leukopenic mice following intraperitoneal or peroral administration.
Architecture of the Yeast Cell Wall
It is concluded that the latter polysaccharide has a central role in the organization of the yeast cell wall and the possible mechanism of synthesis and physiological significance of the cross-links is discussed.
Preparation of microparticulate β‐glucan from Saccharomyces cerevisiae for use in immune potentiation
A microparticulate form of β‐glucan that remains in suspension longer for pharmaceutical applications and has superior immune potentiation characteristics has been developed.