New mechanisms for sulfonylurea control of insulin secretion

@article{Satin1996NewMF,
  title={New mechanisms for sulfonylurea control of insulin secretion},
  author={L. S. Satin},
  journal={Endocrine},
  year={1996},
  volume={4},
  pages={191-198}
}
Oral antidiabetic sulfonylureas like tolbutamide and glyburide have been used to treat patients with noninsulin dependent diabetes mellitus. These agents lower blood glucose by stimulating insulin secretion from the pancreatic islets of Langerhans. A major component of this stimulation is sulfonylurea-mediated closure of the ATP-inhibited potassium channels… CONTINUE READING