New markers for cardiovascular disease risk in women: impact of endogenous estrogen status and exogenous postmenopausal hormone therapy.

@article{Davison2003NewMF,
  title={New markers for cardiovascular disease risk in women: impact of endogenous estrogen status and exogenous postmenopausal hormone therapy.},
  author={Sonia Louise Davison and Susan Ruth Davis},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2003},
  volume={88 6},
  pages={2470-8}
}
The role of estrogen in altering cardiovascular disease risk in women is contentious. Menopause is associated with increased risk for ischemic heart disease and cerebrovascular disease, which collectively are the main causes of morbidity and mortality in women of developed nations. Observational studies suggest a protective role of estrogen, whereas recent randomized controlled trials report a negative role for oral estrogen in primary and secondary prevention of cardiovascular events… CONTINUE READING