New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge.

@article{Rao2003NewMA,
  title={New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge.},
  author={Karumanchi V. Rao and Bernard D Santarsiero and Andrew D. Mesecar and Raymond F Schinazi and Babu L. Tekwani and Mark T. Hamann},
  journal={Journal of natural products},
  year={2003},
  volume={66 6},
  pages={
          823-8
        }
}
Eleven manzamine type alkaloids, two beta-carbolines, and five nucleosides have been isolated from an Indonesian sponge. Among these are the previously characterized 12,34-oxamanzamine A, 12,34-oxamanzamine E, manzamine A (1), 8-hydroxymanzamine A, 6-deoxymanzamine X, manzamine E (2), manzamine X, manzamine F (4), norharman, thymine, 2',3'-didehydro-2',3'-dideoxyuridine, uracil, thymidine, and 2'-deoxyuridine. The structures for the five new compounds have been assigned as 32,33-dihydro-31… CONTINUE READING

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