New isochromophilones VII and VIII produced by Penicillium sp. FO-4164.

@article{Yang1996NewIV,
  title={New isochromophilones VII and VIII produced by Penicillium sp. FO-4164.},
  author={D J Yang and Hiroshi Tomoda and Noriko Tabata and Rokuro Masuma and Satoshi O̅mura},
  journal={The Journal of antibiotics},
  year={1996},
  volume={49 3},
  pages={223-9}
}
New isochromophilones VII and VIII were isolated from the culture broth of Penicillium sp. FO-4164. The structures were elucidated as 6H-2-benzopyran-6,8(7H)-dione, 5-chloro-3-(3',5'-dimethyl-1',3'-heptadienyl)-1,7,8a-trihydro-7, 8a-dihydroxy-7-methyl-7-acetate for isochromophilone VII and 6H-2-benzopyran-6-one,5-chloro-3-(3',5'-dimethyl-1', 3'-heptadienyl)-1,7,8,8a-tetrahydro-7,8-dihydroxy-7-methyl-8-acetate for isochromophilone VIII. Isochromophilones VII and VIII inhibited diacylglycerol… CONTINUE READING